Exparel – a new, long-acting local anesthetic

Exparel – a new, long-acting local anesthetic

Posted on November 6, 2011

Say hello to Exparel. It’s a new form of a local anesthetic that’s been recently approved by the U.S. FDA. Here’s the neat part: a single dose can provide relief for up to 72 hours, which is a big improvement over what we have now.

The product combines the long-acting anesthetic bupivacaine with Pacira’s patented DepoFoam, which allows a slow release of the drug. If the price is right, you can expect to see this used a lot in anesthesia pain blocks, as well as outpatient surgery, such as breast augmentations and tummy tucks.
Exparel has been evaluated in 21 clinical studies, with more than 1,300 participants, and has an excellent safety profile. It should add significantly to post-op comfort, and reduce the need for nausea-causing opiate medications.


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